|
姓 名: |
洪然 |
性别: |
男 |
职称: |
研究员 |
学历: |
研究生 |
电话: |
021-54925161 |
传真: |
021-64166128 |
电子邮件: |
rhong@mail.sioc.ac.cn |
个人主页: |
http://honggroup.sioc.ac.cn |
通讯地址: |
上海市零陵路345号 200032 |
课题组主页: |
http://honggroup.sioc.ac.cn |
简历:
1992–1996,四川大学,物理化学,本科
1996–2001, 中科院上海有机所,理学博士, 导师: 林国强 研究员
2001–2002, University of Houston, 博士后, 导师:Prof. Jay K. Kochi
2002–2007, Brandeis University, 博士后, 导师:Prof. Li Deng
2007–至今, 中科院上海有机所, 研究员, 课题组长
研究方向:
天然产物仿生合成、酶催化和不对称合成方法。致力于将生物合成的策略应用于反应方法学的发展和具有重要生理活性的复杂天然产物全合成研究。
代表论著:
1. Lin Yang, Zuming Lin, Shunjie Shao, Qian Zhao, and Ran Hong*, “Enantioconvergent and Concise Synthesis of Lasonolide A” Angew. Chem., Int. Ed. 2018, 57, Early
View, DOI:10.1002/anie.201811093.
2. Changmin Xie, Jisheng Luo, Yuping Zhang, Sha-Hua Huang, Lili Zhu, and Ran Hong*, "Catalytic Aza-Wacker Annulation: Tuning Mechanism by the Activation Mode of
Amide and Enantioselective Syntheses of Melinonine-E and Strychnoxanthine" Org. Lett. 2018, 20, 2386-2390.
3. Kuan Zheng, Defeng Shen, Ran Hong*, "Bioimetic Synthesis of Lankacidin Antibiotics" J. Am. Chem. Soc. 2017, 139, 12939-12942.
4. Li Zhai, Xuechao Tian, Chao Wang, Qi Cui, Wenhua Li, Sha-Hua Huang*, Zhi-Xiang Yu*, Ran Hong*, "Construction of Morphan Derivatives by Nitroso-Ene Cyclization:
Mechanistic Insight and Total Synthesis of (±)-Kopsone" Angew. Chem., Int. Ed. 2017, 56, 11599-11603.
5. Lin Yang, Zuming Lin, Sha-Hua Huang*, Ran Hong*, "Stereodivergent Synthesis of Functionalized Tetrahydropyrans Accelerated by Mechanism-Based Allylboration
and Bioinspired oxa-Michael Cyclization" Angew. Chem., Int. Ed. 2016, 55, 6280-6284.
6. Jie Ouyang, Rui Yan, Xianwei Mi, Ran Hong*, "Enantioselective Total Synthesis of (?)-Hosieine A" Angew. Chem., Int. Ed. 2015, 54, 10940-10943.
7. Lin Yang, Guoli He, Ruifeng Yin, Lili Zhu, Xiaoxia Wang, Ran Hong*, "Synthesis of Polyketide Stereoarrays Enabled by A Traceless Oxonia–Cope Rearrangement"
Angew. Chem., Int. Ed. 2014, 53, 11600-116004.
8. Lili Zhu, Jisheng Luo, Ran Hong*, "Total Synthesis of (±)-Cafestol: A Late-Stage Construction of the Furan Ring Inspired by A Biosynthesis Strategy" Org. Lett. 2014, 16,
2162-2165.
9. Yan Wang, Kuan Zheng, Ran Hong*, "Chiral Silver Phosphate-catalyzed Cycloisomeric Kinetic Resolution of α-Allenic Alcohols" J. Am. Chem. Soc. 2012, 134, 4096-
4099.
10.Yan Wang, Lili Zhu, Yuying Zhang, Ran Hong*, "Bioinspired and Concise Synthesis of (±)-Stemoamide" Angew. Chem., Int. Ed. 2011, 50, 2787-2790.
课题组合影: