林汉斌--生命过程小分子调控全国重点实验室

研究员

林汉斌/男

学　　历：博士
职　　称：研究员
电　　话：0760-85286866
电子邮件：linhanbin@simm.ac.cn
专家类别：研究员
通讯地址：广东中山翠亨新区中瑞（欧）工业园健康医药示范区
课题组网页：https://simm.cas.cn/sourcedb/zw/gb2020/yjzz/202103/t20210317_5976832.html

简介

2010年本科毕业于北京理工大学生命学院，2014年在加拿大萨斯喀彻温大学医学院获得药理学博士学位。博士毕业后于加拿大渥太华心脏研究所及多伦多大学从事博士后研究，导师是加拿大权威的心血管病医生，多伦多大学医学院教授Peter Liu。主要从事心脏病病理及免疫学的研究。目前研究内容主要包括探究重要免疫因子信号通路在心脏疾病发病机制中的关键作用，以及利用蛋白质组学方法筛选心脏病理条件下的生物标记蛋白。2021被中国科学院上海药物研究所引进，任课题组长，研究员。

研究方向

心脑血管疾病药理，心脑血管疾病病理，心脑血管相关疾病的创新药物研发，线粒体代谢功能

获奖及荣誉

2017/8European Society of Cardiology Congress 2017 travel grant for basic science

2017/8European Society of Cardiology Congress 2017 young investigator award

2017/8Canadian Institutes of Health Research (CIHR) for an Institute Community Support (ICS) Travel Award with the Institute of Circulatory and Respiratory Health

2015/7 - 2017/6Ottawa Heart Institute Cardiac Research Endowed Fellowship

2014/6国家优秀自费留学生奖学金

2013/9Arthur Symth PhD Scholarship

2012/10Canadian Institutes of Health Research Have a Heart Bursary

2012/9James Regan Graduate Scholarship Award in Cardiology Research

2012/6Member of Canadian Cardiovascular Society

2012/6Member of CIHR Institute of Circulatory and Respiratory Health (ICRH) research community

2012/4Canadian Institutes of Health Research (CIHR) for an Institute Community Support (ICS) Travel Award with the Institute of Circulatory and Respiratory Health

2011/10The Graduate Students & Post-Doctoral Fellows Conference Travel Fund

2011/9The College of Medicine Graduate Scholarship

2010/9The University of Saskatchewan Graduate Scholarship

2010/6北京理工大学优秀毕业生

承担科研项目情况

国家重大新药创制科技专项，综合性新药研究开发技术大平台，子课题负责人

代表论著

1. Han-Bin Lin, PhD and Peter P. Liu, MD. (2020). COVID-19 and the Heart, ACE2 Level and the Company it Keeps Hold the Key. JACC: Basic to Translational Science. 5(9): 884-887.

2. Han-Bin Lin, PhD; Kotaro Naito, MD, PhD; Yena Oh, MSc, Gedaliah Farber; BHSc, Georges Kanaan, PhD, Alan Valaperti, PhD; Fayez Dawood, DVM; Liyong Zhang, PhD; Guo Hua Li, MD, PhD; David Smyth, PhD; Mark Moon, MSc; Youan Liu, MD; Wenbin Liang, PhD; Benjamin Rotstein, PhD; Dana Philpott, PhD; Kyoung-Han Kim, PhD; Mary-Ellen Harper, PhD; Peter P Liu, MD. (2020). Innate immune Nod1/RIP2 signaling is essential for cardiac hypertrophy, - but requires mitochondrial antiviral signaling protein (MAVS) for signal transductions and energy balance. Circulation. 2020 Dec 8;142(23):2240-2258

3. Han-Bin Lin, Keshav Sharma, Dariusz Bialy, Magdalena Wawrzynska, Randy Purves, Francisco Cayabyab, Mieczyslaw Wozniak, Grzegorz Sawicki. (2014). Inhibition of MMP-2 expression affects the levels of metabolic enzymes: Proteomic analysis of rat cardiomyocytes. Journal of Proteomics. 106(25): 74-85.

4. Cadete Virgilio JJ*,Lin Han-Bin* , Sawicka Jolanta, Wozniak Mieczyslaw, Sawicki Grzegorz. (2012). Proteomic analysis of right and left cardiac ventricles under aerobic conditions and after ischemia/ reperfusion. Proteomics. 12(14): 2366-2377.

5. Lin Han-Bin, Cadete Virgilio JJ, Sawicka Jolanta, Wozniak Mieczyslaw, Sawicki Grzegorz. (2012). Effect of the myosin light chain kinase inhibitor ML-7 on the proteome of hearts subjected to ischemia/reperfusion injury. Journal of Proteomics. 75(17): 5386-5395.